The field of genomics is in a state of rapid change, driven by multiple inflections in disruptive technologies. Instruments for decoding and digitising the language of biology at ever higher resolutions and in real-time are becoming increasingly accessible, growing genomic databases of human populations, plants, animals, bacteria and viruses at an exponential rate. This has coincided with the rise of transformer models in AI, which, as it turns out, are uniquely suited to understanding connections in vast multi-modal data. Meanwhile the emergence of molecular tools like CRISPR allow us to manipulate at the underlying letters in the DNA and RNA with unprecedented precision. The momentum in these fields is palpable, with new breakthroughs seemingly announced on a weekly basis. We may look back on this decade the Renaissance of genomics and synthetic biology. Click here to download document